Is tTGA more essential in diagnosis of gluten sensitive enteropathy?
A research article to be published on March 21, 2009 in the World Journal of Gastroenterology will address this question. The study shows that GSE patients in the general population may not be identified by clinical features, since a similar percentage of related CD symptoms was found in individuals with positive and negative markers. This fact explains why CD remains underdiagnosed in a high proportion of affected subjects and is an additional argument for mass-screening using other approaches.
You can read the article here: http://www.wjgnet.com/1007-9327/15/1331.asp

